Theoretical constraints on masses of heavy particles in Left-Right Symmetric Models

Left-Right symmetric models with general $g_L \neq g_R$ gauge couplings which include bidoublet and triplet scalar multiplets are studied. Possible scalar mass spectra are outlined by imposing Tree-Unitarity, and Vacuum Stability criteria and also using the bounds on neutral scalar masses $M_{\rm H^{ FCNC}}$ which assure the absence of Flavour Changing Neutral Currents (FCNC). We are focusing on mass spectra relevant for the LHC analysis, i.e., the scalar masses are around TeV scale. As all non-standard heavy particle masses are related to the vacuum expectation value (VEV) of the right-handed triplet ($v_R$), the combined effects of relevant Higgs potential parameters and $M_{\rm H^{ FCNC}}$ regulate the lower limits of heavy gauge boson masses. The complete set of Renormalization Group Evolutions for all couplings are provided at the 1-loop level, including the mixing effects in the Yukawa sector. Most of the scalar couplings suffer from the Landau poles at the intermediate scale $Q \sim 10^{6.5}$ GeV, which in general coincides with violation of the Tree-Unitarity bounds.Comment: 9 pages, 5 figures, pdflatex, Matches published versio

Left-Right Symmetry and the Charged Higgs Bosons at the LHC

The charged Higgs boson sector of the Minimal Manifest Left-Right Symmetric model (MLRSM) is investigated in the context of LHC discovery search for new physics beyond Standard Model. We discuss and summarise the main processes within MLRSM where heavy charged Higgs bosons can be produced at the LHC. We explore the scenarios where the amplified signals due to relatively light charged scalars dominate against heavy neutral $Z_2$ and charged gauge $W_2$ as well as heavy neutral Higgs bosons signals which are dumped due to large vacuum expectation value $v_R$ of the right-handed scalar triplet. In particular, production processes with one and two doubly charged Higgs bosons are considered. We further incorporate the decays of those scalars leading to multi lepton signals at the LHC. Branching ratios for heavy neutrino $N_R$, $W_2$ and $Z_2$ decay into charged Higgs bosons are calculated. These effects are substantial enough and cannot be neglected. The tri- and four-lepton final states for different benchmark points are analysed. Kinematic cuts are chosen in order to strength the leptonic signals and decrease the Standard Model (SM) background. The results are presented using di-lepton invariant mass and lepton-lepton separation distributions for the same sign (SSDL) and opposite sign (OSDL) di-leptons as well as the charge asymmetry are also discussed. We have found that for considered MLRSM processes tri-lepton and four-lepton signals are most important for their detection when compared to the SM background. Both of the signals can be detected at 14 TeV collisions at the LHC with integrated luminosity at the level of $300 fb^{-1}$ with doubly charged Higgs bosons up to approximately 600 GeV. Finally, possible extra contribution of the charged MLRSM scalar particles to the measured Higgs to di-photon ($H_0^0 \to \gamma \gamma$) decay is computed and pointed out.Comment: FCNC analysis is incorporated while fitting the scalar spectrum. Light doubly charged scalars are still compatible with FCNC. Accepted in JHEP. New References and figures are added. The fitted scalar spectrum is given in detail in appendi

Multi-photon signal in supersymmetry comprising non-pointing photon(s) at the LHC

We study a distinct supersymmetric signal of multi-photons in association with jets and missing transverse energy. At least one of these photons has the origin in displaced vertex, thus delayed and non-pointing. We consider a supersymmetric scenario in which the gravitino is the lightest supersymmetric particle (LSP) (with a mass $\sim 1~{keV}$) and the lightest neutralino is the next-to-lightest supersymmetric particle (NLSP). The NLSP decays dominantly into a photon and a gravitino within the detector with a decay length ranging from $c\tau_{\tilde{\chi}}\sim$ 50-100 cm. In addition, we assume that the second lightest neutralino and the lightest neutralino are nearly degenerate and this leads to a prompt radiative decay of the next-to-lightest neutralino into a photon and a lightest neutralino with a large branching ratio. Such degenerate neutralinos can be realised in various representations of the $SU(5)$, $SO(10)$, and $E(6)$ Grand Unified Theories (GUTs). The non-pointing photons can be reconstructed at the electromagnetic calorimeter of the ATLAS inner-detector, which have been designed with good timing and directional resolution. We find that with a centre-of-mass energy $E_{cm}=14 ~{TeV}$ at an integrated luminosity of 100 $fb^{-1}$ one may see evidence of hundreds of tri-photon events and a few four-photons events at the LHC, in addition to several thousands di-photon events. We also predict the event rates even at the early phase of LHC run.Comment: 10 pages; 6 figure

Evolutionary framework with reinforcement learning-based mutation adaptation

Although several multi-operator and multi-method approaches for solving optimization problems have been proposed, their performances are not consistent for a wide range of optimization problems. Also, the task of ensuring the appropriate selection of algorithms and operators may be inefficient since their designs are undertaken mainly through trial and error. This research proposes an improved optimization framework that uses the benefits of multiple algorithms, namely, a multi-operator differential evolution algorithm and a co-variance matrix adaptation evolution strategy. In the former, reinforcement learning is used to automatically choose the best differential evolution operator. To judge the performance of the proposed framework, three benchmark sets of bound-constrained optimization problems (73 problems) with 10, 30 and 50 dimensions are solved. Further, the proposed algorithm has been tested by solving optimization problems with 100 dimensions taken from CEC2014 and CEC2017 benchmark problems. A real-world application data set has also been solved. Several experiments are designed to analyze the effects of different components of the proposed framework, with the best variant compared with a number of state-of-the-art algorithms. The experimental results show that the proposed algorithm is able to outperform all the others considered.</p

Patchy Amphiphilic Dendrimers Bind Adenovirus and Control Its Host Interactions and in Vivo Distribution

The surface of proteins is heterogeneous with sophisticated but precise hydrophobic and hydrophilic patches, which is essential for their diverse biological functions. To emulate such distinct surface patterns on macromolecules, we used rigid spherical synthetic dendrimers (polyphenylene dendrimers) to provide controlled amphiphilic surface patches with molecular precision. We identified an,. I optimal spatial arrangement of these patches on certain dendrimers that enabled their interaction with human adenovirus 5 (Ads). Patchy dendrimers bound to the surface of Ads formed a synthetic polymer corona that greatly altered various host interactions of Ads as well as in vivo distribution. The dendrimer corona (1) improved the ability of Ad5-derived gene transfer vectors to transduce cells deficient for the primary Ad5 cell membrane receptor and (2) modulated the binding of Ads to blood coagulation factor X, one of the most critical virus host interactions in the bloodstream. It significantly enhanced the transduction efficiency of Ad5 while also protecting it from neutralization by natural antibodies and the complement system in human whole blood. Ads with a synthetic dendrimer corona revealed profoundly altered in vivo distribution, improved transduction of heart, and dampened vector sequestration by liver and spleen. We propose the design of bioactive polymers that bind protein surfaces solely based on their amphiphilic surface patches and protect against a naturally occurring protein corona, which is highly attractive to improve Ad5-based in vivo gene therapy applications

Back reaction effects on the dynamics of heavy probes in heavy quark cloud

We holographically study the effect of back reaction on the hydrodynamical properties of $\mathcal{N} = 4$ strongly coupled super Yang-Mills (SYM) thermal plasma. The back reaction we consider arises from the presence of static heavy quarks uniformly distributed over $\mathcal{N} = 4$ SYM plasma. In order to study the hydrodynamical properties, we use heavy quark as well as heavy quark-antiquark bound state as probes and compute the jet quenching parameter, screening length and binding energy. We also consider the rotational dynamics of heavy probe quark in the back-reacted plasma and analyse associated energy loss. We observe that the presence of back reaction enhances the energy-loss in the thermal plasma. Finally, we show that there is no effect of angular drag on the rotational motion of quark-antiquark bound state probing the back reacted thermal plasma.Comment: 29 pages, 21 figure